Aufgaben

• Durchführung und Analyse electrophysiologischer Experimente in vivo.
• Optische Bildgebung und Experimente an perfundierten Herzen.
• Entwicklung genotyp-spezifischer Therapien für Long-QT-Syndrom.

Fähigkeiten

• Interesse an kardialer Elektrophysiologie und tierexperimentellen Modellen.
• Erfahrung mit elektrophysiologischen und optischen Methoden.
• Besitz eines Tierschutzscheins ist erforderlich.

Department of Physiology
01.06.2025 or by agreement
4 years
We are seeking two motivated PhD candidates for our experimental projects on novel precision mechanism-based electrophysiological therapies. With this project, we aim to gain insights into potential QT-normalizing and anti-arrhythmic effects of various peptide molecules known to activate repolarizing ion currents. The ultimate goal is to develop novel mechanisms-based, genotype-specific therapeutic options for the genetic channelopathy long QT syndrome.

• has a strong interest in cardiac electrophysiology and its clinical translation
• has keen interest and experience in experimental animal models
• is in the possession of an animal welfare certificate
• possesses at least basic knowledge in electrophysiological methods, optical techniques and molecular methods

• Challenging and diverse work in a motivated and dynamic team
• High degree of independence
• Use of the university sports facilities
• Attractive workplace close to Bern train station