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The Position

At Roche, we believe it's urgent to deliver medical solutions right now - even as we develop innovations for the future. We are passionate about transforming patients' lives. We are courageous in both decision and action. And we believe that good business means a better world.

That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

As part of the global technical development organization, the Particle Design group is the center of excellence for the design of drug substance particles with tailor-made solid-state properties to facilitate downstream processing to the drug product. This includes the development and optimization of the processes on laboratory scale, as well as scale-up of the corresponding manufacturing processes in close collaboration with the production sites. Our responsibilities also include the evaluation and implementation of new strategies to obtain particles with the desired properties.

As an Intern in the particle design group you will be working on one of the following project-areas:

Project A. Computational Intern Solid State Sciences

This project is intended to further evolve existing software solutions in the realms of solubility prediction, morphology prediction and crystal structure prediction. The project goal includes conducting literature research on new approaches and testing of these in small subprojects.

The (experimental) work is going to focus on: no experimental work expected.

Project B. Industrialization of Spherical Agglomeration/Crystallization Spherical crystallization

This project addresses two main challenges for the development of spherical agglomeration/crystallization processes:

1. Solvent selection: An efficient solvent selection is a crucial step in applying the technology to a new compound.

2. Endpoint determination for bridging liquid addition: Dosage endpoint detection during spherical agglomeration is important for scale-up, as the primary particles may undergo a certain variation heavily impacting the amount of bridging liquid needed to get the desired agglomerate quality.

Who you are

You are a student (or you graduated within 12 months prior the start date) in the subject of chemistry, chemical or process engineering, pharmacy, pharmaceutical sciences, pharmaceutical technology, physics or a related field (preferably with a bachelor's degree) and have an interest and experience in crystallization and solid-state characterization. Furthermore, you are interested in using and sharing your knowledge as part of your internship in a modern working environment.

The (experimental) work is going to focus on: Screening procedure optimization for solvent system selection and spherical agglomeration experiments.

Your further profile for one of the positions:

• General:

  • Team-oriented and decision-making personality

  • Problem solving-oriented work habits

  • Good knowledge of MS-Office (Word, Excel, PowerPoint)

  • Proficient in English, German is a plus

  • Experience working in a lab-environment.

• For project area A: Basic knowledge of crystallization techniques. Basic knowledge of programming (e.g. Perl, Python) and an interest in computational chemistry.

• For project area B: Hands-on experience in various crystallization techniques, formation of emulsions and their stabilization, as well as crystallization techniques.

• For project area C: Basic knowledge of pressure driven filtration technologies, ideally in the area of cross-flow membrane filtration.

• For project area D: Knowledge in process engineering, powder processing, as well as powder characterization techniques.

This internship opportunity is one of a number of positions we offer in the department per semester. The interviews will take place on an interview day with all considered candidates and the whole department.

Your complete application includes the following documents:

• A Current CV and a Motivation Letter
• A certificate of enrollment (if you are currently studying). If you want to use this opportunity to do a Master's or Diploma thesis, please highlight this in your application.
• For Non-EU/EFTA citizens: Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies.

Application deadline is 21.08.2024.

Sustainability is an important aspect for our planet and the people living on it. In order to transform our world to a better one, the United Nations have published 17 Sustainable Development Goals (

https://sdgs.un.org/goals

Assume that you are writing your own grant application for a 12 months internship on the topic sustainability. Select at least one of the 17 goals, relate it to your education/study and propose a project topic for an internship out of it.

During your application, please make sure to upload the following documents:

• Your up-to-date CV
• A certificate of enrollment (if you are currently studying)
• Your cover letter
• Your solution proposal for the task described above (max. 3 slides, pdf)

For Non-EU/EFTA citizens: Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies.

Selected candidates will be invited to a virtual interview day which will take place on 16.10.2024.

The Internship will start in 2025 for 9-12 months, please indicate your preferred start date and duration in your application.

here.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Are you ready to apply? We are looking for someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities.

https://careers.roche.com/global/en/faq

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche's largest sites.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.