Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

The Analytical Development Biochemistry group, located in Basel, is an integral component of how we innovate healthcare through the invention of differentiated medicines for treating diseases of current unmet medical need. This internship program integrates seamlessly into a European-based University degree program, and therefore we offer the most talented students the opportunity to gain valuable work experience with us.

During the internship, your tasks will include:

• Familiarization with a newly purchased 2D-UHPLC System
• Digging into relevant literature regarding 2D-UHPLC method development and share this knowledge in form of presentations and lectures
• Development of an MS based method for the characterization / quantification of degradation products and modifications of biomolecules
• Optimization of the sample preparation (e.g., automation) and the HPLC separation conditions
• Development of 2D-UHPLC separations of Biomolecules
• Comprehensive documentation of performed experiments and developed methods

Who You Are

You are currently enrolled in your Bachelor's studies preferably in Biology / Bio-(analytical) Chemistry / Pharmaceutical Sciences or related and will continue to be enrolled during the entire period of the internship. Alternatively, you are currently enrolled in a Master's program, or you graduated no longer than 12 months ago. Students in their gap year are not eligible.

Due to Swiss regulations, non-EU/EFTA citizens must be enrolled at a university for the entire duration of the internship, and a letter from the university stating that the internship is mandatory for the studies is required. The mandatory letter also has to specify the required duration. Please upload these documents together with your application documents.

If this project is to be used for Bachelor's/Master's thesis, then only if the duration of the internship can be extended by 3 months. You are motivated to increase and share your theoretical and practical knowledge on this emerging and exciting field of liquid chromatography-mass spectrometry (LC-MS) / electrospray ionization mass spectrometry (ESI-MS) and you are an enthusiast of new technologies, and you easily show engagement with people. Experiences in sample preparation of biomolecules and in mass spectrometry in general are considered a plus.

Moreover, you are/have:

• Highly self-motivated and science driven
• Hands-on experiences in the field of UHPLC separation techniques for biomolecules (e.g., SEC, HIC, RPC, IEC etc.)
• Knowledge of Chromatographic Data Systems (preferably Agilent Chemstation/OpenLab)
• Knowledge of mass spectrometry data systems (e.g., Bruker, Waters, Thermo,)
• Knowledge of data evaluation software (e.g., PMI)
• Knowledge about validated CSV system within GMP (Good Manufacturing Practice) environment is a plus
• Excellent German skills - written and verbal

Applications need to include a CV and a motivation letter. Please clearly indicate your preferred starting date and duration of internship (9-12 months) in your cover letter.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.